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An aptamer-linked graphene oxide (GO) microarray is synthesized for multiplex heavy metal ion detection. Fluorescent nanosized GO sheets are micropatterned, and specific aptamers targeting Ag(+) and Hg(2+) are immobilized on the GO array. Upon capture of the target heavy metal ions, electron transfer occurs between the GO (donors) and the heavy metal ions (acceptors), leading to fluorescence quenching of the GO.
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Liu et al. (2013) studied this question.
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