Why the study?
Do arterial pH and pCO2 correlate with quantitative electroencephalographic findings during open heart surgery?
Do arterial pH and pCO2 correlate with quantitative electroencephalographic findings during open heart surgery?
Arterial pH and pCO2 changes measured peripherally during open heart surgery do not correlate with quantitative electroencephalographic findings.
Peripheral pH/pCO2 changes do not correlate with EEG during open heart surgery; leaves open other determinants of cerebral electrical activity.
One hundred and seventy-one estimations of arterial pH and pCO2 were correlated with quantitative electroencephalographic findings during open heart surgery in thirty-four patients. Electroencephalograms could not be related to such fortuitous changes in the pH and pCO2 during open heart surgery as might occur in normal activity of the brain or body. It is not possible to measure the pH of cortex in human studies, and data based on blood flowing from a peripheral artery may not accurately reflect changes in the brain. Also, there may be some mechanisms by which the brain is protected from wideswings of acid-base imbalance.
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Juneja et al. (1972) studied this question.
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