Why the study?
Does preprocedural embolization with Amplatzer plugs improve quality of life compared to coil embolization in patients undergoing endovascular aortic aneurysm repair?
Does preprocedural embolization with Amplatzer plugs improve quality of life compared to coil embolization in patients undergoing endovascular aortic aneurysm repair?
In patients undergoing EVAR, preprocedural internal iliac artery embolization with Amplatzer plugs resulted in higher but not statistically significant quality of life scores compared to coil embolization.
No significant QOL difference between Amplatzer plugs and coils after EVAR; leaves open embolization choice and requires randomized trials.
Purpose: To determine if there were differences in quality of life (QOL) within the first year following EVAR for patients undergoing internal iliac embolization depending on the type of device used. Methods: Patients who underwent endovascular AAA repair were identified using a Vascular surgery database at a tertiary care center from 2002-2008. The Radiology Information System and Image Viewer were then used to identify patients who underwent preprocedural embolization prior to endovascular aneurysm repair. Nine patients had embolization with nester coils, 9 had embolization with the amplatzer vascular plug, a type of nitinol based self expanding device. Another group of 8 patients who did not undergo preprocedural embolization was used as a comparator group. These patients were contacted via telephone and answered questions regarding QOL post procedure. The Australian Vascular QOL was the tool used to measure QOL. Differences in QOL were tabulated between the groups of patients. Results: Of the 9 patients who underwent embolization with amplatzer plug, the median QOL score was 60 (p value 0.575), the median QOL for the nester coil group was 52.5 and the comparator group was 58. Separate analysis was done dividing patients into two groups, with and without comorbidities without statistical significance. Conclusion: Patients who underwent preprocedural embolization using amplatzer plugs compared to coils had higher overall QOL scores although the difference was not significant.
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Khan et al. (2011) studied this question.
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