Key points are not available for this paper at this time.
H. H. Chen, S. W. Duffy, Laszlo Tabar, A Markov Chain Method to Estimate the Tumour Progression Rate from Preclinical to Clinical Phase, Sensitivity and Positive Predictive Value for Mammography in Breast Cancer Screening, Journal of the Royal Statistical Society. Series D (The Statistician), Vol. 45, No. 3 (1996), pp. 307-317
Chen et al. (1996) studied this question.