Key result
Resection of primary pleural synovial sarcoma in a 15-year-old boy was followed by tumor recurrence at 20 months.
Case Report (n=1)
Primary pleural synovial sarcoma is a rare entity that can recur after resection.
Recurrence at 20 months after resection suggests prolonged surveillance may be warranted; leaves open optimal adjuvant strategies for this rare pediatric entity.
Synovial sarcoma (SS) is an uncommon soft tissue tumor that occurs primarily in the extremities of young adults, especially in the periarticular region. In this report, we describe the rare occurrence of primary SS of the pleura in a 15-year-old boy. Histologically, the tumor demonstrated monophasic morphologic findings and showed positive staining with vimentin and Bcl-2 and focally for cytokeratin CK7. Fluorescent in situ hybridization identified t(X;18) translocation. The patient developed recurrences 20 months following resection of the tumor. The literature on this uncommon entity is reviewed, and its histogenesis, differential diagnoses, and cytologic features are also discussed.
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Ng et al. (2003) conducted a case report in Primary pleural synovial sarcoma (n=1). Resection was evaluated on Recurrence. Resection of primary pleural synovial sarcoma in a 15-year-old boy was followed by tumor recurrence at 20 months.
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