The marked growth inhibition of A vena coleoptile sections caused by 100 mg streptomycin/1 was prevented when man-ganous ions were added to the test solution. Pretreatment with Mn++ had only a slight effect on SM inhibition, and post-treatment was ineffective. Other cations and various organic compounds were without activity comparable to that of Mn++ in preventing the streptomycin inhibition of growth. Mn++ did not reduce streptomycin inhibition of the growth of E. coli “B” in liquid culture.
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Walter G. Rosen (1954) studied this question.
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