Most of the sulfobromophthalein sodium (BSP) appearing in the bile of man, rat, dog, sheep and cat differs chromatographically from the free BSP originally administered (1-4). The altered BSP compounds in man, rat and dog appear to be anmino acid conjugates Thus, after hydrolysis of the major BSP compounds with 6 N HC1, several amino acids have been detected by filter paper chromatography. Glycine, glutamic acid and ala- nine were identified in man (2, 3), glycine and glutamic acid in the rat (2) and glycine in the dog (3).
No takes yet. Share an insight, caveat, or question.
Combes et al. (1960) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: