Key result
Higher thoracic impedance linked to lower delivered electrical current during successful cardioversion.
Why the study?
Conventional empirical energy selection for DCCV does not consider individual factors and may lead to unnecessary electrical damage.
Does human thoracic impedance impact the electrical current required for successful direct current cardioversion in patients with atrial arrhythmias?
Observational (n=466)
No
Does human thoracic impedance impact the electrical current required for successful direct current cardioversion in patients with atrial arrhythmias?
Human thoracic impedance, which is higher in females and patients with higher BMI, significantly impacts the electrical current required for successful direct current cardioversion in atrial arrhythmias.
May inform energy selection for women and higher-BMI patients; leaves open whether impedance-guided protocols improve outcomes.
Background and Objectives: Direct current cardioversion (DCCV) is a safe and useful treatment for atrial tachyarrhythmias. In the past, the energy delivered in DCCV was decided upon empirically, based only on the type of tachyarrhythmia. This conventional method does not consider individual factors and may lead to unnecessary electrical damage. Materials and Methods: We performed DCCV in patients with atrial tachyarrhythmias. The impedance and electrical current at the moment of shock were measured. The human thoracic impedance between both defibrillator patches and the electric current that was used were measured. Results: A total of 683 DCCVs were performed on 466 atrial tachyarrhythmia patients. The average impedance was 64 ± 11 Ω and the average successful current was 23 ± 6 mA. The magnitude of the electrical current that was successful depended upon the human impedance (linear regression, B = −0.266, p < 0.001) and the left atrial diameter (B = 0.092, p < 0.001). Impedance was directly proportional to body mass index (BMI) (B = 1.598, p < 0.001) and was higher in females than in males (77 ± 15 Ω vs. 63 ± 11 Ω, p < 0.001). Notably, the high-impedance (>70 Ω) group had a higher BMI (27 ± 4 kg/m2 vs. 25 ± 3 kg/m2, p < 0.001) and a higher proportion of females (37% vs. 9%, p < 0.001) than the low-impedance group (<70 Ω). However, thoracic impedance was not an independent predictor for successful DCCV. Conclusions: Human thoracic impedance was one of the factors that impacted the level of electrical current required for successful DCCV in patients with atrial arrhythmias. In the future, it will be helpful to consider individual predictors, such as BMI and gender, to minimize electrical damage during DCCV.
No takes yet. Share an insight, caveat, or question.
Roh et al. (2021) conducted an observational in Symptomatic atrial arrhythmias (atrial tachycardia, atrial flutter, paroxysmal/persistent/long-standing persistent atrial fibrillation) (n=466). Human thoracic impedance during direct current cardioversion (high impedance ≥70 Ω) vs. Low thoracic impedance (<70 Ω) was evaluated on Magnitude of electrical current delivered for successful restoration of sinus rhythm (B = -0.266, r = -0.593, p=<0.001). Human thoracic impedance was inversely associated with the electrical current required for successful cardioversion (B = -0.266, p < 0.001) and increased with female sex and higher BMI.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: