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Self-assembled monolayers on silicon oxide surfaces functionalized with a unimolecular DNA G-quadruplex derived from the thrombin binding aptamer have been prepared. The formation of the G-quadruplex in the presence of potassium ions is observed by atomic force microscopy (AFM). The results presented here are interesting for the fabrication of nanostructured systems for sensing applications
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Manning et al. (2011) studied this question.
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