Chronic motor neuropathies: response to interferon-beta 1a after failure of conventional therapies

4 patients with chronic motor neuropathies (3 with multifocal motor neuropathy, 1 with pure motor form of chronic inflammatory demyelinating polyneuropathy) not improving after conventional treatments such as immunoglobulins, steroids, cyclophosphamide or plasma exchange.

Interferon-beta 1a 6 MIU subcutaneous injections three times a week for 6-12 months.

Disability assessed using the nine hole peg test, the 10 metres walking test, and the modified Rankin scale.surrogate