Key result
A 55-year-old female presented with a rare case of locally advanced, synchronous malignancies of the gallbladder and head of the pancreas, uniquely accompanied by alopecia totalis.
Why the study?
Synchronous gallbladder and pancreas malignancies are extremely rare, and alopecia totalis as a presenting feature of an abdominal malignancy has never been reported.
Case Report (n=1)
This case report highlights a very rare presentation of synchronous gallbladder and pancreas malignancies associated with alopecia totalis.
Rare synchronous gallbladder-pancreatic cancers with alopecia totalis warrant diagnostic vigilance; leaves open paraneoplastic associations for further study.
A 55-year-old female presented with history of pain in the right hypochondrium along with complete loss of facial and scalp hair over last two months. On evaluation, she was found to have locally advanced, synchronous malignancies of the gallbladder and head of the pancreas. Synchronous malignancy of gallbladder and pancreas is in itself very rare and less than 10 such cases have been reported in the world literature. Alopecia totalis has been classically associated with various autoimmune disorders. However, alopecia totalis as a presenting feature of any abdominal malignancy has never been reported in the medical literature. The present report describes a rare association of synchronous pancreatobiliary malignancies with strange clinical presentation.
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Kumar et al. (2023) conducted a case report in Synchronous pancreas and gallbladder cancer with concomitant alopecia totalis (n=1). A 55-year-old female presented with a rare case of locally advanced, synchronous malignancies of the gallbladder and head of the pancreas, uniquely accompanied by alopecia totalis.
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