Why the study?
Vitamin B12 deficiency may cause cardiac autonomic dysfunction, endothelial dysfunction, reduced ejection fraction, and myocardial deformation, but its effect on pediatric cardiac electrical activity needed investigation.
Does B12 vitamin deficiency affect Tp-e and QT dispersion values in children?
Observational
Does B12 vitamin deficiency affect Tp-e and QT dispersion values in children?
This study aims to evaluate the impact of vitamin B12 deficiency on cardiac electrical activity, specifically Tp-e and QT dispersion, in a pediatric population.
B12 deficiency may alter repolarization indices in children; hypothesis-generating and requires prospective trials before clinical consideration.
Aim: B12 vitamin deficiency may cause cardiac autonomic dysfunction, heart rate variability, endothelial dysfunction and subclinical atherosclerosis, a significant degree of reduction in heart ejection fraction and deformation of the left ventricular myocardium. We aimed to investigate the effect of B12 deficiency in children on cardiac electrical activity by comparing the Tp-e and QT dispersion values between healthy children and children with B12 deficiency.
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Solak et al. (2021) conducted an observational in B12 Vitamin Deficiency. B12 Vitamin Deficiency vs. Healthy children was evaluated on Tp-e and QT dispersion values.
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