What question did this study set out to answer?

Compare epidemiologic and clinicopathologic characteristics between naturally acquired and experimentally induced SIVmac infections in macaques.

February 1, 1990Journal of Medical Primatology

Comparative Biology of Natural and Experimental SIVmac Infection in Macaque Monkeys: A Review

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Authors

NKNorval W. KingTufts University LCLaura V. ChalifouxNew England Biolabs (United States)DRD J RinglerNew England Biolabs (United States)

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Implication

Comparative review reveals severe meningoencephalomyelitis in experimental versus natural SIVmac infection in macaques, highlighting critical differences in disease pathology.

Key Points

Compare epidemiologic and clinicopathologic characteristics between naturally acquired and experimentally induced SIVmac infections in macaques.
Analyzed epidemiologic and clinicopathologic records from 11 macaques with naturally acquired SIV infection (10 deceased).
Compared findings to autopsy and clinical data from 34 rhesus monkeys that died following experimental SIVmac infection.
Meningoencephalomyelitis occurred in 41% of experimentally infected rhesus monkeys but was completely absent in naturally infected macaques.
Variations in sex distribution, age at death, and types of opportunistic infections were identified between groups, largely attributable to experimental conditions.

Cite This Study

King et al. (1990) studied this question.

synapsesocial.com/papers/6a75e5e04555d8f90b70727d https://doi.org/10.1111/j.1600-0684.1990.tb00418.x

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Implication

Comparative review reveals severe meningoencephalomyelitis in experimental versus natural SIVmac infection in macaques, highlighting critical differences in disease pathology.

Comparative Biology of Natural and Experimental SIVmac Infection in Macaque Monkeys: A Review

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparative Biology of Natural and Experimental SIVmac Infection in Macaque Monkeys: A Review

Discussion

Member takes

Implication

Key Points

Cite This Study

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