What question did this study set out to answer?

This research aims to understand how uncomplicated intimal dissection affects restenosis rates after coronary angioplasty.

September 1, 1985Circulation

Influence of intimal dissection on restenosis after successful coronary angioplasty.

View Full Paper

Ask AI

Bookmark

Why the study?

Does uncomplicated intimal dissection influence the rate of angiographic restenosis in patients after successful coronary angioplasty?

Population

986 patients who underwent follow-up angiography after successful percutaneous transluminal coronary…

Comparison

Presence of uncomplicated intimal dissection… vs Absence of intimal dissection after PTCA

Design

Cohort

Follow-up

mean 7 +/- 5 months

Authors

PLPierre P. LeimgruberWashington State University Spokane GRGary S. RoubinInterventional Cardiology HAH. Vernon AndersonInterventional Cardiology

Discussion

Member takes

Implication

Uncomplicated intimal dissection after PTCA was not associated with higher restenosis; leaves open possible benefit with low gradients but should not yet change practice.

Key Points

This research aims to understand how uncomplicated intimal dissection affects restenosis rates after coronary angioplasty.
Analyzed data from 986 patients who underwent percutaneous transluminal coronary angioplasty (PTCA).
Follow-up angiography assessed the presence of intimal dissection and restenosis rates after a mean of 7 months.
Divided patients based on final transstenotic pressure gradients into two subgroups (≥15 mm Hg and <15 mm Hg).
Restenosis rate was 30% without intimal dissection and 24% with it (p = .08).
In patients with gradients of 15 mm Hg or less, restenosis was 19% with intimal dissection versus 28% without (p < .05).
For gradients greater than 15 mm Hg, no significant differences in restenosis rates were found (35% vs 39%, p = NS).

Structured PICO

Does uncomplicated intimal dissection influence the rate of angiographic restenosis in patients after successful coronary angioplasty?

Population

986 patients who underwent follow-up angiography after successful percutaneous transluminal coronary angioplasty (PTCA)

Intervention

Presence of uncomplicated intimal dissection after PTCA

Comparator

Absence of intimal dissection after PTCA

Outcome

Angiographic restenosis rate at follow-upsurrogate

Uncomplicated intimal dissection after successful PTCA does not increase, and may even reduce, the risk of angiographic restenosis, particularly when associated with a favorable hemodynamic result.

Cite This Study

Leimgruber et al. (1985) studied this question.

synapsesocial.com/papers/6a75ee8320e137e1c11630ca https://doi.org/10.1161/01.cir.72.3.530

View Full Paper

Ask AI

Bookmark

Implication

Uncomplicated intimal dissection after PTCA was not associated with higher restenosis; leaves open possible benefit with low gradients but should not yet change practice.

Influence of intimal dissection on restenosis after successful coronary angioplasty.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Influence of intimal dissection on restenosis after successful coronary angioplasty.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider