Why the study?
Does transoesophageal atrial pacing improve conversion to normal sinus rhythm and reduce arrhythmias compared to direct current cardioversion in patients with refractory atrial flutter?
Does transoesophageal atrial pacing improve conversion to normal sinus rhythm and reduce arrhythmias compared to direct current cardioversion in patients with refractory atrial flutter?
Transoesophageal atrial pacing is as effective as direct current cardioversion for terminating refractory atrial flutter, with a significantly lower risk of post-procedural arrhythmias.
Transoesophageal atrial pacing matches direct current cardioversion for conversion but reduces post-procedure arrhythmias; supports its consideration as a safer alternative in refractory flutter.
OBJECTIVE: To compare the safety and efficacy of transoesophageal atrial pacing (TAP) with an easily swallowed pill electrode and direct current cardioversion (DCC) in patients with atrial flutter that was refractory to appropriate medical treatment. DESIGN: Prospective, randomised clinical trial. SETTING: Community based United States naval hospital. SUBJECTS: Twenty one consecutive patients with refractory atrial flutter selected consecutively from the inpatient cardiology consultation service. All patients were haemodynamically stable and medical treatment with a class IA or IC antiarrhythmic agent had failed. Eleven patients were treated with TAP and 10 patients were treated with DCC. INTERVENTIONS: Digoxin was given to all patients to control the ventricular rate to < 100/minute. MAIN OUTCOME MEASURE: Conversion to normal sinus rhythm and arrhythmias after cardioversion. RESULTS: Conversion to normal sinus rhythm was similar in both groups (TAP 8/11, DCC 9/10, p = 0.31). Arrhythmias after cardioversion including third degree heart block and non-sustained ventricular tachycardia were more frequent in the DCC group (TAP 0/11, DCC 6/10, p = 0.02). CONCLUSION: Transoesophageal atrial pacing with an easily swallowed pill electrode is safe, well tolerated, and is as efficacious as DCC for refractory atrial flutter.
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Tucker et al. (1993) studied this question.
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