Key result
Bilateral PCA thrombectomy followed by non-surgical management with apixaban and clopidogrel led to improvement of symptoms in a 36-year-old female with a massive left ventricular thrombus.
Why the study?
Left ventricular thrombus is a major complication of acute myocardial infarction, highlighting the need to review its pathogenesis, diagnosis, and treatment.
Case Report (n=1)
This case highlights the critical need for monitoring and appropriate anticoagulation of left ventricular thrombus post-myocardial infarction to prevent severe embolic complications such as bilateral posterior cerebral artery stroke.
Chronic LVT can cause bilateral embolic stroke years post-MI; hypothesis-generating for surveillance and anticoagulation duration.
Left ventricular thrombus (LVT) is a major complication of acute myocardial infarction (MI). Here, we describe the case of a 36-year-old female with a history of acute anterior MI six years prior to hospitalization, who presented with bilateral vision loss due to a bilateral embolic posterior cerebral artery (PCA) stroke in the setting of a 5.7 x 1.7 cm LVT. She underwent bilateral PCA thrombectomy, which led to improvement of her symptoms. Her LVT was managed non-surgically with apixaban and clopidogrel. Her case highlights the need for more medical education about LVT, as quick initiation of anticoagulation is essential in improving outcomes. We review the existing literature to explain the pathogenesis, diagnosis, and treatment of LVT.
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Jain et al. (2022) conducted a case report in Left ventricular thrombus causing bilateral posterior cerebral artery stroke (n=1). Bilateral PCA thrombectomy followed by apixaban and clopidogrel was evaluated on Improvement of symptoms. Bilateral PCA thrombectomy followed by non-surgical management with apixaban and clopidogrel led to improvement of symptoms in a 36-year-old female with a massive left ventricular thrombus.
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