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January 1, 1996Biochemistry

Heme Oxygenase (HO-1):  His-132 Stabilizes a Distal Water Ligand and Assists Catalysis

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Authors

AWAngela WilksUniversity of Maryland, BaltimorePMPaul R. Ortiz de MontellanoUniversity of California, San FranciscoJSJie SunShanghai Lixin University of Accounting and Finance

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Cite This Study

Wilks et al. (1996) studied this question.

synapsesocial.com/papers/6a75fcd151ada088e8786a3ahttps://doi.org/10.1021/bi952405f
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Degradation of heme by a soluble peptide of heme oxygenase obtained from rat liver microsomes by mild trypsinization1991 · 49 citations
  2. 2Haem degradation in human haemoglobin in vitro. Separation of the contribution of the α- and β-subunits1984 · 10 citations
  3. 3Heme Oxygenase His25Ala Mutant: Replacement of the Proximal Histidine Iron Ligand by Exogenous Bases Restores Catalytic Activity1995 · 63 citations
  4. 4Human heme oxygenase cDNA and induction of its mRNA by hemin1988 · 320 citations
  5. 5Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible.1986 · 759 citations