The Predictive Value of Tissue Doppler for Left Ventricular Recovery and Remodeling after Primary Percutaneous Coronary Intervention

50 consecutive patients with acute ST-segment elevation myocardial infarction (STEMI) who were candidates for primary PCI. Exclusions included past history of ischemic heart disease, prior thrombolytic therapy, valvular disease, cardiomyopathy, significant left ventricular hypertrophy, pericardial disease, abnormal ECG (bundle branch block, pre-excitation, atrial fibrillation, atrial flutter, or complete AV block), or prior coronary artery bypass surgery.

Primary percutaneous coronary intervention (PCI) resulting in good reperfusion criteria (TIMI 3 flow, myocardial blush grade 2 or 3, ST-segment resolution ≥50%, and early peaking of cardiac biomarkers).

Primary percutaneous coronary intervention (PCI) resulting in poor reperfusion criteria (TIMI 0, 1, or 2 flow, myocardial blush grade 0 or 1, ST-segment resolution <50%, and absence of early peaking of cardiac biomarkers).

Left ventricular functional recovery (defined as an increase of 5% or more in LVEF) and left ventricular remodeling (defined as an increase in LVEDV >20% or LVESV >15%) at one month follow-up.surrogate