Personalizing Approaches to Management of HPV+ Oropharyngeal Cancer

HPV+ oropharyngeal cancer represents a unique disease entity in the realm of head and neck cancer with distinct incidence and prevalence, pathogenesis, and treatment outcome. Management of this disease needs to be personalized in consideration of a combination of factors of both patient and disease characteristics. Overall outcomes in this patient population are excellent. Therefore, late side effects of treatment are gaining increasing importance and attention. Here we present a brief overview of personalized approaches for this patient population, illustrated by a discussion of several cases.