Why the study?
Understanding of the origin and evolution of hepatitis D virus has been poor due to a historical lack of data on similar viruses, until the recent discovery of delta-like agents in vertebrate and invertebrate species.
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Design
Review
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New delta-like agents revise HDV evolutionary models; leaves open zoonotic origins and therapeutic implications.
Hepatitis D (delta, δ) virus (HDV) was discovered more than 40 years ago, but the understanding of its origin and evolution is poor. This is mainly due to the lack, until recently, of data on the existence of any viruses similar to HDV. The discovery in recent years of sequences of new delta-like agents in a wide range of vertebrate (Vertebrata) and invertebrate (Invertebrata) species has facilitated a revision of views on the origin of HDV and contributed to understanding the place of this unique virus among other animals' viral agents. The purpose of this review is to analyze the latest published data on new delta-like agents and their biological characteristics.
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Исаева et al. (2021) studied this question.
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