Answers are grounded in this paper and cite their sources.
Herein we report the specific labelling of the epigenetic modification 5-hydroxymethyl-cytosine along genomic DNA molecules with a fluorescent reporter molecule. Enzymatic glucosylation followed by a click chemistry reaction enables single molecule detection as well as global quantification of 5hmC in genomic DNA.
No takes yet. Share an insight, caveat, or question.
Michaeli et al. (2013) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: