Synergistic extraction has been demonstrated for nickel(II) with 5,8-diethyldodecan-6-oxime-7-ol (DEHO), the active component of LIX63 and a range of carboxylic acids including aliphatic and aromatic derivatives. The synergism was shown to depend on the nature of the carboxylic acid with a linear dependance between the pKa of the acid and the synergistic coefficient as defined by the difference in pH50 between that obtained by the mixture of extractants and that of DEHO along.
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Castresana et al. (1988) studied this question.