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The preparation of nanoparticles with sufficient chemical and thermal stability for bio-related applications has long been a major issue in nanobiotechnology. New types of highly stable Au, CdSe/ZnS, and F3O4 nanoparticles have been stabilized with Tween derivatives through coordination to the particle surface as well as van der Waals interaction with the primary ligands on the nanoparticle surface. The Au nanoparticles are more stable than the corresponding Au nanoparticles functionalized with thiolated DNA.
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Rongchao Jin (2008) studied this question.
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