Why the study?
Does the prosthetic valve to sinus of Valsalva index predict the need for permanent pacemaker implantation in patients undergoing TAVR?
Does the prosthetic valve to sinus of Valsalva index predict the need for permanent pacemaker implantation in patients undergoing TAVR?
The prosthetic valve size to diameter of sinus of Valsalva index derived from pre-procedural CT is a significant predictor of the need for permanent pacemaker implantation after TAVR.
May aid PPM risk stratification post-TAVR; leaves open prospective validation before clinical adoption.
BACKGROUND: Cardiac conduction abnormalities requiring permanent pacemaker (PPM) implantation are major complications of transcatheter aortic valve replacement (TAVR). We aimed to investigate whether the relationship between prosthetic valve size and cardiac-gated computed tomography (CT)-based aortic root complex measurements can aid in recognizing patients at risk for PPM implantation post-TAVR. METHODS: We included 83 of 114 consecutive patients who underwent TAVR with the Edwards Sapien valve (Edwards Lifesciences, Irving, CA, USA) at our institution. We excluded patients with preexisting PPM, patients who required conversion to an open surgical procedure, and patients without CT data. We assessed the significance of various potential predictors of PPM placement post-TAVR. RESULTS: Following TAVR, eight patients (9.6%) required PPM. Prosthetic valve to sinus of Valsalva (SOV) index was significantly higher in those patients requiring a PPM post-TAVR (84.1 ± 9.3 vs 76.8 ± 7.1, P = 0.009). CONCLUSIONS: The prosthetic valve size to diameter of SOV index was identified as a novel predictor of PPM implantation after TAVR.
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Routh et al. (2017) studied this question.
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