We report the fabrication of single-chain polymer nanoparticles (SCNP) that can reversibly undergo a coil to particle transition via formation and cleavage of intramolecular disulfide cross-links. Characterization of this behaviour via shifts in SEC retention time confirm the changes in solution conformation in response to oxidative or reductive stimuli.
No takes yet. Share an insight, caveat, or question.
Tuten et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: