Scrub Typhus as a Cause of Acute Encephalitis Syndrome, Gorakhpur, Uttar Pradesh, India

Of the acutely ill patients who had positive mIFA results, 67% had pathognomonic eschars, confirming the clinical diagnostic value in this sign of systemic infection. Thrombocytopenia as a sign of scrub typhus could be useful but is a less specific diagnostic indicator (9). There was only a 75% agreement between the rapid test kit and the precise mIFA, but RDTs were shown to be more useful in early detection