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July 16, 2014Pediatric RheumatologyOpen Access

Development of positive antinuclear antibodies and rheumatoid factor in systemic juvenile idiopathic arthritis points toward an autoimmune phenotype later in the disease course

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BHBoris HügleGerman Center for Pediatric and Adolescent RheumatologyCHClaas HinzeUniversity Hospital MünsterELElke LainkaEssen University Hospital

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Hügle et al. (2014) studied this question.

synapsesocial.com/papers/6a763c443025cdd732bcb320https://doi.org/10.1186/1546-0096-12-28
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ANTIBODIES TO HISTONES H1 AND H5 IN SERA OF PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS1989 · 35 citations
  2. 2Anakinra as first‐line disease‐modifying therapy in systemic juvenile idiopathic arthritis: Report of forty‐six patients from an international multicenter series2010 · 466 citations
  3. 3Prevalence and sociodemographic correlates of antinuclear antibodies in the United States2012 · 458 citations