A modified kroni the initial studies of Takamatsu and Gomori,5* 8 , s has proved convenicnt for the histochemical locakation of acid and alkaline phosphatases in a variety of tissues. Data of practical value in the differentiation of lesions have been obtained.7 Metastatic prostatic carcinonia can be readily identi-fied2 and the influence of steroids on glandular-tissue enzymes deiiionstrated.4 Some unique tumors that defy complete histological appraisal can be e ~a l u a t e d . ~
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George W. Changus (1957) studied this question.
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