Ochratoxin A is a nephrotoxic secondary metabolite of several fungal species included in the genera Aspergillus and Penicillium . A radioimmunoassay for this toxin is described. The reagents included antibodies against a coupling product of ochratoxin A and bovine IgG. 125 I‐labelled egg‐albumin‐ochratoxin A was employed as radioactive antigen. Free ochratoxin A dissolved in phosphate‐buffered saline inhibited immunoprecipitation of the radioactive antigen. The procedure showed a lower limit of detection at 20 ppb of ochratoxin A.
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Aalund et al. (1975) studied this question.
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