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October 12, 2015Molecular CancerOpen Access

Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine

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Authors

MYMing-Chen YangThe Ohio State UniversityHWHao‐Chen WangNational Cheng Kung UniversityYHYa-Chin HouNational Cheng Kung University

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Yang et al. (2015) studied this question.

synapsesocial.com/papers/6a764507dd478a52beb1bc3bhttps://doi.org/10.1186/s12943-015-0449-3
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells2012 · 381 citations
  2. 2Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance2012 · 97 citations