1.) Values for total body chloride, as determined by radiobromine83 dilution, averaged 51.1 meq/kg body weight for a series of normal newly born infants. Total body chloride, on a per kilogram basis is far higher in young infants than adults. 2.) Values obtained by this method show excellent agreement with those obtained by earlier workers employing direct chemical analysis. Therefore, the bromide dilution method would appear to be valid for the measurement of total body chloride in young infants.
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Forbes et al. (1953) studied this question.