Water, the flexibility of the maltose molecule, and sugar/arene interactions are responsible for the equilibrium between a folded (I) and nonfolded (II) conformation in a glycophane (III is an intermediate). Glycophanes are cyclodextrin-cyclophane hybrids, which are of interest as models of receptors.
No takes yet. Share an insight, caveat, or question.
Morales et al. (1998) studied this question.