Why the study?
Association of quadricuspid aortic valve with ascending aortic aneurysms is rare, prompting investigation into the behavior and biomechanical characteristics of the aorta in this setting.
The biomechanical properties of an ascending aorta associated with a quadricuspid aortic valve resemble those of a bicuspid aortic valve but feature greater wall thickness.
Aortic surveillance may be considered with QAV; leaves open biomechanical mechanisms and need for larger studies.
Association of quadricuspid aortic valve (QAV) with ascending aortic aneurysms (AsAA) is rare. A 63-year-old female with hypertension was found (on MRI) to have an ascending aortic aneurysm (52 mm in maximum diameter) and dilatation at the level of the sinotubular junction (38 mm in diameter) associated with quadricuspid aortic valve. An ascending aortic wall replacement surgery was performed. In this study, we focus on the behavior of the aorta associated with QAV considering the in vitro biomechanical characteristics and histology. The properties of QAV are closer to bicuspid aortic valve than tricuspid aortic valve, but with higher wall thickness.
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Lin et al. (2022) studied this question.
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