Why the study?
Does tirofiban reduce microembolic signals in patients with recent cerebral or retinal embolism of arterial origin?
Population
24 patients with recent cerebral or retinal embolism of arterial origin and a microembolic signal rate >6…
Comparison
Tirofiban infusion vs Baseline and post-infusion
Design
Case_series
Authors
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May suppress microembolic signals in arterial embolism; hypothesis-generating for antiplatelet strategies, requiring randomized confirmation before practice change.
Does tirofiban reduce microembolic signals in patients with recent cerebral or retinal embolism of arterial origin?
Tirofiban completely blocks cerebral microembolism in patients with recent arterial embolism, demonstrating that these emboli are predominantly composed of platelet-fibrinogen units.
Junghans et al. (2003) studied this question.
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