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A growing body of evidence supports the intranasal administration of atomized medications for a wide variety of pediatric indications. This article describes their use applicable to orthopedic specialists in the areas of pediatric pain management, as well as pre- and intraoperative sedation. As a quick, painless alternative to more invasive routes of administration, intranasal drug delivery has shown similar time to clinical effect compared to the intravenous route, while minimizing anxiety in both patients and their parents.
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Warrington et al. (2011) studied this question.
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