Nickel Catalysts/N,N′-Bidentate Directing Groups: An Excellent Partnership in Directed C–H Activation Reactions

This review focuses on chelation-assisted regioselective C–H activation with C–C or/and C–N bond formation using nickel(0) or -(II) as the catalysts, where bidentate directing groups play a key role in the successful transformation. A 2-pyridinylmethylamine or an 8-aminoquinoline moiety are the more powerful auxiliaries among the directing groups examined.