A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models

Despite intensive epidemiological investigation over many decades in many parts of the world, the geographical distribution and the true prevalence and incidence of MS remain uncertain. In recent years a clearer understanding of the distribution of MS has emerged, though debate continues and uncertainties remain. Variations in prevalence have Chapter 1 * From a cross section of 1099 MS patients at final review From 363 patients in a prevalence survey From 780 patients attending University of British Columbia MS Clinic From Veteran's Administration hospital admissions (A) and World War 2 veterans (B) according to Kurtzke From 301 (of 441) patients in a prevalence survey ** From 254 patients in a cohort study n/k, not known * No relapses or progression of disability RR disease without or with progression of disability unresolved 6 months after a relapse