Conically shaped nanopores prepared by anisotropic etching of heavy-ion-tracked polymer films are an especially promising type of abiotic nanopore for biosensing applications. We have discovered that the cone angle of conical nanopores (see Figure) prepared by the track-etch method can be systematically varied by varying the transmembrane potential difference applied during pore etching.
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Harrell et al. (2005) studied this question.
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