Why the study?
Does multiple sclerosis patient serum block evoked electric activity differently than normal human serum in cerebral neocortex cultures?
Population
Serum samples from 13 multiple sclerosis patients and 10 normal human volunteers applied to cerebral…
Comparison
Application of multiple sclerosis patient sera vs Application of normal human sera
Design
Preclinical
Authors
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Serum neuroelectric blocking is a nonspecific property unrelated to MS pathogenesis; leaves open any role in demyelinating disease.
Does multiple sclerosis patient serum block evoked electric activity differently than normal human serum in cerebral neocortex cultures?
The ability to block evoked electric responses in tissue cultures is a nonspecific serum property not specifically related to the pathogenesis of demyelinating disease.
Seil et al. (1976) studied this question.
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