Answers are grounded in this paper and cite their sources.
Simultaneous reduction of the activation energy for the exo reaction and increase of that for the endo reaction explain how a cyclic porphyrin trimer that can bind diene 1 and dienophile 2 in its cavity increases the exo selectivity of a Diels–Alder reaction and accelerates it dramatically.
No takes yet. Share an insight, caveat, or question.
Walter et al. (1995) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: