Gas chromatography systems with coupled columns in a multidimensional (MD) mode have become more important for the analysis of complex mixtures, due to the increased selectivity that can be achieved by the use of multiple columns with differing stationary phases. Coupling two or more detectors can also help to increase the information content of the analysis. This review presents the various strategies used in multidimensional gas chromatography (MDGC), with Fourier transform infrared (FT-IR) and/or mass spectrometric (MS) detection, with an emphasis on applications of these techniques for analysis of components in complex matrices.
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Tomlinson et al. (1996) studied this question.
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