This report describes the application of a computer‐aided column design and optimization program to the analysis of purgeable compounds in waste water. Series‐coupled columns with dissimilar phases can be “selectivity‐tuned” to provide the maximum separation factors, thus facilitating the most rapid analysis. A computer program calculates the column lengths and operating conditions which are required to provide the desired resolution at a specified flow rate.
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Villalobos et al. (1991) studied this question.
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