A new internal charge transfer (ICT) fluorescent probe for highly selective and sensitive monitoring of H(2)S has been developed. The design takes advantage of the facile reduction of non-fluorescent hydroxyamine naphthalimide by H(2)S to highly fluorescent amine naphthalimide. It has been demonstrated that the probe is able to detect H(2)S at submicromolar concentrations in cells.
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Xuan et al. (2012) studied this question.
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