Why the study?
Does systemic administration of central serotonergic agents increase the repetitive extrasystole threshold in the canine ventricular myocardium?
Does systemic administration of central serotonergic agents increase the repetitive extrasystole threshold in the canine ventricular myocardium?
Central serotonergic agents increase the threshold for repetitive electrical activity in a canine model, suggesting they may inhibit arrhythmogenic sympathetic nerve traffic from the brain to the heart.
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Increases repetitive extrasystole threshold in canine model; leaves open whether central serotonergic agents suppress human ventricular arrhythmias.
Blatt et al. (1979) studied this question.
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