Background Biomaterials are defined as substances intended to replace a part of the body or its function in a secure, safe and economical way, while being physiologically and aesthetically acceptable. Biomaterials can be bioinert or regenerative. Biocompatibility refers to the ability of a material to elicit a specific biological response after administration in a living organism. Measuring the biocompatibility of materials used in dentistry is not an easily achievable task. Methods Scientific databases – PubMed, Scopus and Medline, as well as monographs, textbooks on the topic, websites were used to search for the data required. The following keywords were used: biomaterials, biocompatibility, dental medicine, medicine, toxicity. The aim of the following article is to summarize the main conclusions authors in the field have reached to when discussing biocompatibility and tolerance of material and products used in medicine and dental medicine. Results and discussion In depth results and discussion are presented in the section. Materials used in medicine and dental medicine encompass a wide range of compounds, with different chemical and physical structures. Therefore, profound knowledge is needed to be able to treat the patients and keep them safe as much as possible from possible adverse biological reactions. Conclusions Medical and dental specialists should pay special attention to the content of the materials they implement in their treatment plans on a daily basis. Being profoundly informed on the general diseases, medications usage and allergic status of their patients can prevent adverse complications. Although medicine explores and studies in depth possible biological reactions, still they may occur.
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Stoykov et al. (2022) studied this question.
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