Key result
Intramuscular injections during childhood acute viremia were identified as a probable cause of provocative poliomyelitis, accounting for 35.65% (n=41) of the surveyed subjects with paralysis.
Why the study?
Are intramuscular injections during acute childhood viremia associated with post-polio residual paralysis?
Cross-Sectional (n=115)
Are intramuscular injections during acute childhood viremia associated with post-polio residual paralysis?
Intramuscular injections during acute childhood viremia may provoke poliomyelitis and subsequent residual paralysis, highlighting the need to avoid unnecessary injections.
May warrant caution with injections during childhood viremia; leaves open causality pending prospective confirmation.
Intramuscular injections can provoke muscular paralysis especially, if the child has had exposure to polio virus. The purpose of the study was to determine the association with known risk factors for motor disabilities in two remote villages of North Karnataka (India), where an increased number of disabled people among select communities had been reported. A community based survey was conducted. The selection of study subjects was done through screening, history related with occurrence of musculoskeletal disability, screening and general examination of the affected joints and muscles. Data analysis was done by estimation of percentages. Among the physical disabilities identified, the most common was post-polio residual paralysis. 35.65% (n = 41) subjects had developed paralysis following the administration of an intramuscular injection when they had acute viremia in childhood, indicating that (probably) muscle paralysis would have been provoked by intramuscular injections, resulting in provocative poliomyelitis. Unnecessary injection must be avoided in children during acute viremia state and use of oral polio vaccine should be encouraged.
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Narayan et al. (2011) conducted a cross-sectional in Post-polio residual paralysis (n=115). Intramuscular injections during acute viremia in childhood was evaluated on Development of paralysis (provocative poliomyelitis). Intramuscular injections during childhood acute viremia were identified as a probable cause of provocative poliomyelitis, accounting for 35.65% (n=41) of the surveyed subjects with paralysis.
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