Key result
Atrial fibrillation was associated with a twofold higher prevalence of vascular dementia compared to controls without atrial fibrillation (21.4% vs 10.7%, P=0.024).
Why the study?
Does atrial fibrillation increase the prevalence of specific dementia subtypes, and is the Hachinski ischemic score accurate in this population?
Population
309 consecutive patients evaluated for cognitive status at an Ambulatory Geriatric Clinic, including 103…
Comparison
Atrial fibrillation (exposure) vs No atrial fibrillation (matched controls)
Design
Case-control
Authors
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AF may warrant closer vascular dementia monitoring in older adults; leaves open Hachinski score accuracy for subtype discrimination.
Case-Control (n=309)
No
Does atrial fibrillation increase the prevalence of specific dementia subtypes, and is the Hachinski ischemic score accurate in this population?
Absolute Event Rate: 21.4% vs 10.7%
p-value: p=0.024
Atrial fibrillation is associated with a higher prevalence of vascular dementia and Alzheimer's disease, but the Hachinski ischemic score is a poor tool for discriminating dementia subtypes in these patients.
Nisio et al. (2014) conducted a case-control in Cognitive impairment and atrial fibrillation (n=309). Atrial fibrillation vs. No atrial fibrillation was evaluated on Prevalence of vascular dementia (p=0.024). Atrial fibrillation was associated with a twofold higher prevalence of vascular dementia compared to controls without atrial fibrillation (21.4% vs 10.7%, P=0.024).
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