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October 1, 2004Cancer ResearchOpen Access

Development of an Autocrine Neuregulin Signaling Loop with Malignant Transformation of Human Breast Epithelial Cells

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Authors

QLQunfang LiGanzhou People's HospitalSASharlin AhmedGlaxoSmithKline (United Kingdom)JLJeffrey A. LoebUniversity of Illinois Chicago

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Li et al. (2004) studied this question.

synapsesocial.com/papers/6a774467df493903fd1ecb98https://doi.org/10.1158/0008-5472.can-04-1152
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Xenograft Model of Progressive Human Proliferative Breast Disease1993 · 210 citations
  2. 2Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin‐like growth factor‐I in human mammary epithelial cells1995 · 63 citations
  3. 3Enhanced expression of heregulin in c-erb B-2 and c-Ha-ras transformed mouse and human mammary epithelial cells1996 · 21 citations
  4. 4Neuregulin-Heparan-sulfate Proteoglycan Interactions Produce Sustained erbB Receptor Activation Required for the Induction of Acetylcholine Receptors in Muscle2001 · 84 citations