Rats with bilateral lateral hypothalamic lesions die of starvation in approximately 7 days after surgery. Rats that were treated with alpha-methyl-p-tyrosine for 3 days prior to lateral hypothalamic surgery spontaneously eat, drink, and gain weight after surgery. These data suggest that recovery of function after lateral hypothalamic damage involves denervation supersensitivity.
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Glick et al. (1972) studied this question.
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