Key result
COVID-19 was an independent strong predictor of aspiration thrombectomy in STEMI patients and was associated with a lower likelihood of optimal TIMI 3 flow despite intensive treatment (P=0.001).
Why the study?
COVID-19 exacerbates coronary intravascular thrombosis in STEMI, motivating an analysis of its impact on the application and effect of thrombectomy.
Does COVID-19 infection affect the application and procedural efficacy of aspiration thrombectomy in patients with STEMI?
Observational (n=29,915)
Yes
Does COVID-19 infection affect the application and procedural efficacy of aspiration thrombectomy in patients with STEMI?
p-value: p== 0.001
COVID-19 infection in STEMI patients is associated with a higher likelihood of requiring aspiration thrombectomy, more severe clinical presentation, and worse angiographic outcomes despite intensive antithrombotic therapy.
COVID-19 positivity was associated with higher thrombectomy rates in STEMI; leaves open whether routine use improves outcomes.
Introduction: Coronavirus disease 2019 (COVID-19) exacerbates intravascular thrombosis that occurs in the coronary artery in ST-elevation myocardial infarction (STEMI). Aim: To analyze the impact of COVID-19 on the application and effect of thrombectomy in STEMI patients. Material and methods: 29915 STEMI patients were analyzed, of whom 3139 (10.5%) underwent thrombectomy. COVID-19 (+) was reported in 311 (10.8%). The clinical characteristics and management of STEMI in COVID-19 (+) and COVID-19 (-) patients were compared. A multivariable logistic regression analysis was performed in search of factors influencing thrombectomy. Results: = 0.001). Conclusions: STEMI patients undergoing aspiration thrombectomy who were COVID-19 (+) were more likely to be in a severe clinical condition (higher Killip class, more frequent cardiac arrest before the procedure) than COVID-19 (-) patients. Despite more intensive antiplatelet and anticoagulant treatment, PCI procedures were less likely to result in an optimal TIMI 3 effect. COVID-19 is an independent strong predictor of patient qualification for aspiration thrombectomy in STEMI.
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Zając et al. (2023) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=29,915). COVID-19 infection vs. COVID-19 (-) was evaluated on Application of aspiration thrombectomy and optimal TIMI 3 effect (p== 0.001). COVID-19 was an independent strong predictor of aspiration thrombectomy in STEMI patients and was associated with a lower likelihood of optimal TIMI 3 flow despite intensive treatment (P=0.001).
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